Annotation Overview for fig|269483.3.peg.4639 in Burkholderia cepacia R18194:
Serine hydroxymethyltransferase (EC 2.1.2.1)

current assignment	Serine hydroxymethyltransferase (EC 2.1.2.1)	EC Number	2.1.2.1
taxonomy id	269483	contig	269483.3:NC_007509 (1,395,070bp)269483.3:NC_007510 (3,694,127bp)269483.3:NC_007511 (3,587,083bp)
internal links	genome browser | feature evidence | sequence	ACH Annotation Clearinghouse (ACH) The Annotation Clearinghouse offers a mapping of genes which are identical in sequence except for the start region (due to differences in start calling). [?]	show essentially identical genes
annotation history		run tool	Psi-BlastTMpredTMHMMGram negative PSORTGram negative SignalPGram positive PSORTGram positive SignalPLipoPInterProScanRadarPPSearchGram negative CELLOGram positive CELLOProDomPDB
FigFam	FIG000040
data base cross references (dbxref)	NCBI: 97050472 CMR: NTL02BSA0712 NCBI: 78065369 NCBI: 77966114 UniProt: GLYA3_BURS3 RefSeq: YP_368138.1 UniProt: Q39J72

Annotation History (history of similar genes)

Date	Annotator	Annotation
9/2/2005	annotation_repair	Annotation for existing assignment Glycine/serine hydroxymethyltransferase
9/2/2005	annotation_repair	Set FIG function to Glycine/serine hydroxymethyltransferase
10/21/2005	OlgaV	Set FIG function to Serine hydroxymethyltransferase (EC 2.1.2.1)

We have assigned the function "Serine hydroxymethyltransferase (EC 2.1.2.1)" to the encoded protein. The protein occurs in 7 subsystems: "Flavohaemoglobin", "Folate Biosynthesis", "Glycine Biosynthesis", "Glycine and Serine Utilization", "Glycine cleavage system", "Serine-glyoxylate cycle", and "Serine Biosynthesis". The function of genes having the same functional roles have been described in Salmonella enterica (2134182, 6325301) and Campylobacter jejuni (2060796). These are homologous proteins which implement the same function.

The chromosomal region of the focus gene (top) is compared with four similar organisms. The graphic is centered on the focus gene, which is red and numbered 1. Sets of genes with similar sequence are grouped with the same number and color. Genes whose relative position is conserved in at least four other species are functionally coupled and share gray background boxes. The size of the region and the number of genomes may be reset. Click on any arrow in the display to refocus the comparison on that gene. The focus gene always points to the right, even if it is located on the minus strand.